10-1030 Coffee and registration

Welcome by Axel Thomson (Edinburgh) and David Hudson (York)

1030-1115 “Prostate cancer trials and translational research”
Johann de Bono. The Institute of Cancer Research, The Royal Marsden hospital, Sutton, Surrey.
Chairs: David Hudson (York), Alastair Lamb (Cambridge)

1115-1200 “Prostate-derived exosomes: treasure chests for prostate cancer biomarkers”
Guido Jenster. Josephine Nefkens Institute, Erasmus University, Rotterdam, The Netherlands.
Chairs: Charlotte Bevan (Imperial College London), Hayley Whitaker (Cambridge)

1200-1300 Selected talks from Abstracts
Chairs: Luke Gaughan (Newcastle), Mick Brown (Manchester)

SAGE and MPSS Profiling of Stroma to Identify Regulators of Prostate Development and Tumourigenesis.
Brigid Orr (Edinburgh)

siRNA Target Selection using Machine Learning Techniques: Genes Implicated in Aggressive Prostate Cancer.
Matthew Parker (ICR, Sutton)

GLI1 induces a program of regression that confers a basal/stem-like and androgen-independent phenotype upon LNCaP prostate cancer cells.
Graham Neill (Queen Mary University of London)

The novel cancer testis antigen T21 is over expressed in prostate cancer and is positively associated with increasing tumor grade and stage.
Amanda Miles (Nottingham)

Functional regulation of the collagen remodelling receptor Endo180 by osteoblastic interactions in metastatic prostate cancer bone lesions.
Justin Sturge (Imperial College London)

Src kinase activation is up-regulated in hormone refractory prostate cancer.
Joanne Edwards (Glasgow)

Wnt-11 promotes neuroendocrine-like differentiation, survival and migration of prostate cancer cells.
Pinar Uysal-Onganer (Imperial College London)

Identification of metabolic enzymes essential for survival of prostate cancer cells by functional studies
Claudio Santos (CRUK, London)

1300-1500 Lunch and poster session

1420-1455 Optional: Solexa technology – what it can and can’t do for you
Stephen Watt, Nik Matthews, Gordon Brown (all CRUK, Cambridge)
Chair: Ian Mills (Cambridge)

1500-1550 Grant applications and career development session
Chairs: Greg Brooke (Imperial College London) Claire Hastie (Portsmouth)

An introduction to CRUK funding and fellowships: Ben Onwuegbusi. Research Manager, CRUK
An Introduction to Prostate UK: Amanda Mclean. Prostate UK
Emma Halls. Prostate Cancer Research Foundation

1550-1600 Coffee

1600-1645 “Forty challenging years of androgen action: from sucrose gradients to proteomics”
Albert Brinkmann. Department of Endocrinology & Reproduction, Erasmus University Medical Centre, Rotterdam, The Netherlands.
Chairs: Amanda Swain (ICR, Fulham), Robert Kypta (Imperial College London)

1645-1700 Prizegiving and close of meeting
Axel Thomson (Edinburgh) and Hayley Whitaker (Cambridge)

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